CAMK4 Antibody

ArtNr	CSB-PA614976ESR2HU-50ul
Hersteller	Cusabio
Menge	50 ul
Quantity options	100 ul 50 ul
Kategorie	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling Neural Adhesion Molecules Antibodies Immunoprecipitation Western Blot ELISA Primary Antibodies Stem Cell Markers
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IP, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Brain Ca(2+) calmodulin dependent protein kinase type 4 antibody; Brain Ca(2+) calmodulin dependent protein kinase type IV antibody; Brain Ca++-calmodulin dependent protein kinase type IV antibody; Calcium / calmodulin dependent protein kinase type 4 catalytic chain antibody; Calcium / calmodulin dependent protein kinase type IV catalytic chain antibody; Calcium/calmodulin dependent protein kinase IV antibody; Calcium/calmodulin dependent protein kinase type IV antibody; Calcium/calmodulin-dependent protein kinase type IV antibody; CAM kinase 4 antibody; CAM kinase GR antibody; CAM kinase IV antibody; CAM kinase-GR antibody; CaMK 4 antibody; CAMK GR antibody; CaMK IV antibody; Camk4 antibody; CaMKGR antibody; IV antibody; KCC4_HUMAN antibody; MGC36771 antibody
Similar products	CAMK4, Calcium/calmodulin-dependent protein kinase type IV (CaMK IV) (EC 2.7.11.17) (CaM kinase-GR), CAMK CAMK-GR CAMKIV
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	CAMK4
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	Brain Ca(2+) calmodulin dependent protein kinase type 4 antibody; Brain Ca(2+) calmodulin dependent protein kinase type IV antibody; Brain Ca++-calmodulin dependent protein kinase type IV antibody; Calcium / calmodulin dependent protein kinase type 4 catalytic chain antibody; Calcium / calmodulin dependent protein kinase type IV catalytic chain antibody; Calcium/calmodulin dependent protein kinase IV antibody; Calcium/calmodulin dependent protein kinase type IV antibody; Calcium/calmodulin-dependent protein kinase type IV antibody; CAM kinase 4 antibody; CAM kinase GR antibody; CAM kinase IV antibody; CAM kinase-GR antibody; CaMK 4 antibody; CAMK GR antibody; CaMK IV antibody; Camk4 antibody; CaMKGR antibody; IV antibody; KCC4_HUMAN antibody; MGC36771 antibody
Immunogen Species	Human
Immunogen	Recombinant Human Calcium/calmodulin-dependent protein kinase type IV protein (304-473AA)
Dilution	ELISA:1:2000-1:10000 WB:1:1000-1:5000 IP:1:200-1:2000
Background	Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK4 signaling cascade and regulates, mainly by phosphorylation, the activity of several transcription activators, such as CREB1, MEF2D, JUN and RORA, which play pivotal roles in immune response, inflammation, and memory consolidation. In the thymus, regulates the CD4+/CD8+ double positive thymocytes selection threshold during T-cell ontogeny. In CD4 memory T-cells, is required to link T-cell antigen receptor (TCR) signaling to the production of IL2, IFNG and IL4 (through the regulation of CREB and MEF2). Regulates the differentiation and survival phases of osteoclasts and dendritic cells (DCs). Mediates DCs survival by linking TLR4 and the regulation of temporal expression of BCL2. Phosphorylates the transcription activator CREB1 on 'Ser-133' in hippocampal neuron nuclei and contribute to memory consolidation and long term potentiation (LTP) in the hippocampus. Can activate the MAP kinases MAPK1/ERK2, MAPK8/JNK1 and MAPK14/p38 and stimulate transcription through the phosphorylation of ELK1 and ATF2. Can also phosphorylate in vitro CREBBP, PRM2, MEF2A and STMN1/OP18.
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Antigen Affinity Purified
General Research Areas	Neuroscience
Initial Research Areas	Neuroscience
Antigen Species	Human
Antigen	Recombinant Human Calcium/calmodulin-dependent protein kinase type IV protein (304-473AA)
Clonality	Polyclonal

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Menge: 50 ul

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Lieferung vsl. bis 18.09.2025

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