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BNIP3 Antibody

ArtNr CSB-PA618642ESR1HU-50ul
Hersteller Cusabio
Menge 50 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen IF, IHC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias BCL2 Adenovirus E1B 19kDa Interacting Protein 3 antibody,BCL2/adenovirus E1B 19 kDa protein interacting protein 3 antibody,BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 antibody,BNIP 3 antibody,BNIP3 antibody,BNIP3_HUMAN antibody,NIP 3 antibody,NIP3 antibody
Similar products BNIP3, NIP3, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Manufacturer - Targets
BNIP3
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
BCL2 Adenovirus E1B 19kDa Interacting Protein 3 antibody, BCL2/adenovirus E1B 19 kDa protein interacting protein 3 antibody, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 antibody, BNIP 3 antibody, BNIP3 antibody, BNIP3_HUMAN antibody, NIP 3 antibody, NIP3 antibody
Immunogen Species
Human
Immunogen
Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 protein (1-164AA)
Dilution
ELISA:1:2000-1:10000
IHC:1:20-1:200
IF:1:50-1:200
Background
Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method
Antigen Affinity Purified
General Research Areas
Cell Biology
Initial Research Areas
Cell Biology
Antigen Species
Human
Antigen
Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 protein (1-164AA)
Clonality
Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: In stock
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