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FZR1 Antibody

ArtNr CSB-PA892473LA01HU-50ug
Hersteller Cusabio
Menge 50 ug
Quantity options 100 ug 20 ug 50 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IHC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CDC20 like 1b antibody,CDC20 like protein 1 antibody,CDC20-like protein 1 antibody,CDC20C antibody,CDH1 antibody,Cdh1/Hct1 homolog antibody,Fizzy related protein 1 antibody,Fizzy related protein antibody,Fizzy related protein homolog antibody,Fizzy-related protein homolog antibody,Fizzy/cell division cycle 20 related 1 antibody,FYR antibody,FZR 1 antibody,FZR 2 antibody,Fzr antibody,FZR_HUMAN antibody,Fzr1 antibody,Fzr1 protein antibody,FZR2 antibody,HCDH 1 antibody,HCDH antibody,hCDH1 antibody,KIAA1242 antibody
Similar products FZR1, Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1), CDH1 FYR FZR KIAA1242
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200
Manufacturer - Targets
FZR1
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
CDC20 like 1b antibody, CDC20 like protein 1 antibody, CDC20-like protein 1 antibody, CDC20C antibody, CDH1 antibody, Cdh1/Hct1 homolog antibody, Fizzy related protein 1 antibody, Fizzy related protein antibody, Fizzy related protein homolog antibody, Fizzy-related protein homolog antibody, Fizzy/cell division cycle 20 related 1 antibody, FYR antibody, FZR 1 antibody, FZR 2 antibody, Fzr antibody, FZR_HUMAN antibody, Fzr1 antibody, Fzr1 protein antibody, FZR2 antibody, HCDH 1 antibody, HCDH antibody, hCDH1 antibody, KIAA1242 antibody
Immunogen Species
Human
Immunogen
Recombinant Human Fizzy-related protein homolog protein (1-493AA)
Dilution
ELISA:1:2000-1:10000
WB:1:500-1:2000
IHC:1:20-1:200
Background
Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage checkpoint: its dephosphorylation and reassociation with the APC/C leads to the ubiquitination of PLK1, preventing entry into mitosis.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method
>95%, Protein G purified
General Research Areas
Cell Biology
Initial Research Areas
Cell Biology
Antigen Species
Human
Antigen
Recombinant Human Fizzy-related protein homolog protein (1-493AA)
Clonality
Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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