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AVEN Antibody

ArtNr CSB-PA335882-50ul
Hersteller Cusabio
Menge 50 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias 1700013A01Rik antibody; 1700056A21Rik antibody; Apoptosis caspase activation inhibitor antibody; AVEN antibody; AVEN_HUMAN antibody; Cell death regulator Aven antibody; mAven L antibody; mAven S antibody; MGC124011 antibody; OTTMUSP00000016129 antibody; PDCD12 antibody; Programmed cell death 12 antibody; RP23-52C15.2 antibody
Similar products apoptosis, caspase activation inhibitor
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Targets
AVEN
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
1700013A01Rik antibody; 1700056A21Rik antibody; Apoptosis caspase activation inhibitor antibody; AVEN antibody; AVEN_HUMAN antibody; Cell death regulator Aven antibody; mAven L antibody; mAven S antibody; MGC124011 antibody; OTTMUSP00000016129 antibody; PDCD12 antibody; Programmed cell death 12 antibody; RP23-52C15.2 antibody
Immunogen Species
Human
Immunogen
Synthetic peptide of human AVEN
Dilution
ELISA:1:2000-1:5000
WB:1:500-1:2000
IHC:1:25-1:100
Background
AVEN, a cell death regulator, is an important signal inducer in acute leuke-mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf-1 mediated apoptosis by interfering with Apaf-1's ability to self-associate. Bcl-2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be detected in other tissues. Erythropoietin and methylprednisolone may play important roles in the expression of AVEN in cardiac tissue, especially after a traumatic brain injury. In young patients suffering from acute lymphoblastic leukemia (ALL), AVEN expression may be a useful tool in prognosis prediction.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method
Antigen affinity purification
General Research Areas
Cell Biology
Initial Research Areas
Cell Biology
Antigen Species
Human
Antigen
Synthetic peptide of Human AVEN
Clonality
Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: In stock
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Lieferung vsl. bis 09.10.2025 

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