ABL1 Antibody

Polyclonal Antibody

ABL1

Abelson murine leukemia viral oncogene homolog 1 antibody, Abelson tyrosine protein kinase 1 antibody, Abl 1 antibody, ABL antibody, ABL proto oncogene 1 non receptor tyrosine kinase antibody, ABL1 antibody, ABL1_HUMAN antibody, bcr/abl antibody, bcr/c abl oncogene protein antibody, c ABL antibody, c abl oncogene 1 non receptor tyrosine kinase antibody, c abl oncogene 1 receptor tyrosine kinase antibody, c ABL1 antibody, JTK7 antibody, p150 antibody, Proto oncogene tyrosine protein kinase ABL1 antibody, Proto-oncogene c-Abl antibody, Tyrosine-protein kinase ABL1 antibody, v abl Abelson murine leukemia viral oncogene homolog 1 antibody, v abl antibody

Fusion protein of human ABL1

The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9, 22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.

Antigen Affinity Purified

Signal Transduction

Fusion protein of Human ABL1