TEAD4 Antibody

Polyclonal Antibody

TEAD4

EFTR 2 antibody, EFTR2 antibody, hRTEF 1B antibody, hRTEF1B antibody, MGC9014 antibody, OTTHUMP00000238119 antibody, OTTHUMP00000238122 antibody, OTTHUMP00000238124 antibody, Related to TEF 1 antibody, Related to TEF1 antibody, Related transcription enhancer factor 1B antibody, RTEF1 antibody, TCF13L1 antibody, TEA domain family member 4 antibody, TEAD 4 antibody, TEAD-4 antibody, TEAD4 antibody, TEAD4_HUMAN antibody, TEF 3 antibody, TEF3 antibody, TEFR 1 antibody, TEFR1 antibody, Transcription factor 13 (SV40 transcriptional enhancer factor) like 1 antibody, Transcription factor 13 like 1 antibody, Transcription factor 13-like 1 antibody, Transcription factor RTEF 1 antibody, Transcription factor RTEF-1 antibody, Transcription factor RTEF1 antibody, Transcriptional enhancer factor 1 related antibody, Transcriptional enhancer factor 3 antibody, Transcriptional enhancer factor TEF 3 antibody, Transcriptional enhancer factor TEF-3 antibody, Transcriptional enhancer factor TEF3 antibody

Recombinant Human Transcriptional enhancer factor TEF-3 protein (74-434AA)

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.

>95%, Protein G purified

Epigenetics and Nuclear Signaling

Recombinant Human Transcriptional enhancer factor TEF-3 protein (74-434AA)