CDK6 Antibody

Polyclonal Antibody

CDK6

CDK 6 antibody, CDK6 antibody, CDK6_HUMAN antibody, Cell division protein kinase 6 antibody, Crk 2 antibody, Crk2 antibody, Cyclin dependent kinase 6 antibody, Cyclin-dependent kinase 6 antibody, MCPH12 antibody, MGC59692 antibody, p40 antibody, PLSTIRE antibody, Serine/threonine protein kinase PLSTIRE antibody, Serine/threonine-protein kinase PLSTIRE antibody, STQTL11 antibody

Fusion protein of human CDK6

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Antigen Affinity Purified

Cell Biology

Fusion protein of Human CDK6