HIF1AN Antibody

ArtNr	CSB-PA959614-50ul
Hersteller	Cusabio
Menge	50 ul
Quantity options	100 ul 50 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DKFZp762F1811 antibody,Factor inhibiting HIF-1 antibody,Factor inhibiting HIF1 antibody,FIH 1 antibody,FIH-1 antibody,FIH1 antibody,FLJ20615 antibody,FLJ22027 antibody,HIF1AN antibody,HIF1N_HUMAN antibody,Hypoxia inducible factor 1 alpha inhibitor antibody,Hypoxia inducible factor 1 alpha subunit inhibitor antibody,Hypoxia inducible factor asparagine hydroxylase antibody,Hypoxia-inducible factor 1-alpha inhibitor antibody,Hypoxia-inducible factor asparagine hydroxylase antibody,Peptide aspartate beta dioxygenase antibody
Similar products	alpha subunit inhibitor, hypoxia inducible factor 1
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB, IHC; ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:50-1:300
Manufacturer - Targets	HIF1AN
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	DKFZp762F1811 antibody, Factor inhibiting HIF-1 antibody, Factor inhibiting HIF1 antibody, FIH 1 antibody, FIH-1 antibody, FIH1 antibody, FLJ20615 antibody, FLJ22027 antibody, HIF1AN antibody, HIF1N_HUMAN antibody, Hypoxia inducible factor 1 alpha inhibitor antibody, Hypoxia inducible factor 1 alpha subunit inhibitor antibody, Hypoxia inducible factor asparagine hydroxylase antibody, Hypoxia-inducible factor 1-alpha inhibitor antibody, Hypoxia-inducible factor asparagine hydroxylase antibody, Peptide aspartate beta dioxygenase antibody
Immunogen Species	Human
Immunogen	Synthetic peptide of human HIF1AN
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:2000 IHC:1:50-1:300
Background	Factor inhibiting HIF-1 (FIH-1) exists as a homodimer and binds to HIF-1alpha. Specifically, FIH-1 operates as an asparaginyl hydroxylase. It catalyzes the hydroxylation of the beta-carbon of Asparagine residue 803 within the carboxy terminal transactivation domain of HIF-1alpha. This hydroxylation event blocks the association of HIF-1alpha with co-activators. FIH-1 also binds to von Hippel-Lindau (VHL) tumor suppressor protein, which represses transcriptional ac-tivity of HIF-1alpha. In transiently transfected human osteosarcoma cells, FIH-1 localizes to the cytoplasm.
Buffer	pH7.4 of PBS, 0.05% NaN3, 40% Glycerol.
Purification Method	Antigen Affinity Purified
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Synthetic peptide of Human HIF1AN
Clonality	Polyclonal

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