TGFB2 Antibody

Polyclonal Antibody

TGFB2

BSC-1 cell growth inhibitor antibody, BSC1 cell growth inhibitor antibody, Cetermin antibody, G-TSF antibody, Glioblastoma-derived T-cell suppressor factor antibody, GTSF antibody, LAP antibody, Latency-associated peptide antibody, MGC116892 antibody, MGF antibody, Milk growth factor antibody, Polyergin antibody, TGF-beta-2 antibody, TGF-beta2 antibody, TGFB2 antibody, TGFB2_HUMAN antibody, Transforming growth factor beta 2 antibody

Synthetic peptide of human TGFB2

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1, 7)(q41, p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.

Antigen Affinity Purified

Human

Polyclonal