RB1 Antibody

ArtNr	CSB-PA232358-50ul
Hersteller	Cusabio
Menge	50 ul
Quantity options	100 ul 50 ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Immunofluorescence Senescence Primary Antibodies Astrocytoma By Organ Bladder Cancer Immunostaining Bone Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Exon 17 tumor GOS561 substitution mutation causes premature stop antibody,GOS563 exon 17 substitution mutation causes premature stop antibody,OSRC antibody,Osteosarcoma antibody,p105-Rb antibody,P105RB antibody,PP105 antibody,pp110 antibody,PPP1R130 antibody,pRb antibody,Prepro retinoblastoma associated protein antibody,Protein phosphatase 1 regulatory subunit 130 antibody,Rb antibody,RB transcriptional corepressor 1 antibody,RB_HUMAN antibody,RB1 antibody,RB1 gene antibody,Retinoblastoma 1 antibody,Retinoblastoma suspectibility protein antibody,Retinoblastoma-associated protein antibody
Similar products	retinoblastoma 1
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000
Manufacturer - Targets	RB1
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	Exon 17 tumor GOS561 substitution mutation causes premature stop antibody, GOS563 exon 17 substitution mutation causes premature stop antibody, OSRC antibody, Osteosarcoma antibody, p105-Rb antibody, P105RB antibody, PP105 antibody, pp110 antibody, PPP1R130 antibody, pRb antibody, Prepro retinoblastoma associated protein antibody, Protein phosphatase 1 regulatory subunit 130 antibody, Rb antibody, RB transcriptional corepressor 1 antibody, RB_HUMAN antibody, RB1 antibody, RB1 gene antibody, Retinoblastoma 1 antibody, Retinoblastoma suspectibility protein antibody, Retinoblastoma-associated protein antibody
Immunogen Species	Human
Immunogen	Fusion protein of human RB1
Dilution	ELISA:1:1000-1:2000 WB:1:200-1:1000
Background	The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma
Buffer	pH7.4 of PBS, 0.05% NaN3, 40% Glycerol.
Purification Method	Antigen Affinity Purified
General Research Areas	Cell Biology
Initial Research Areas	Cell Biology
Antigen Species	Human
Antigen	Fusion protein of Human RB1
Clonality	Polyclonal

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