MYH11 Antibody

Polyclonal Antibody

MYH11

AAT4 antibody, DKFZp686D10126 antibody, DKFZp686D19237 antibody, FAA4 antibody, FLJ35232 antibody, MGC126726 antibody, MGC32963 antibody, MYH 11 antibody, MYH11 antibody, MYH11_HUMAN antibody, Myosin 11 antibody, Myosin heavy chain 11 antibody, Myosin heavy chain 11 smooth muscle antibody, Myosin heavy chain antibody, Myosin heavy chain smooth muscle isoform antibody, Myosin heavy polypeptide 11 smooth muscle antibody, Myosin-11 antibody, SMHC antibody, SMMHC antibody, smooth muscle isoform antibody, Smooth muscle myosin heavy chain 11 isoform SM2 antibody, Smooth muscle myosin heavy chain isoform SM2 antibody

Synthetic peptide of human MYH11

The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified.

Antigen Affinity Purified

Signal Transduction

Synthetic peptide of Human MYH11