MCM8 Antibody

ArtNr	CSB-PA936890-50ul
Hersteller	Cusabio
Menge	50 ul
Quantity options	100 ul 50 ul
Kategorie	Antibodies Cell Biology Cell Status Western Blot ELISA Proliferation Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	C20orf154 antibody; dJ967N21.5 antibody; DNA helicase MCM8 antibody; DNA replication licensing factor MCM8 antibody; MCM8 antibody; MCM8_HUMAN antibody; MGC119522 antibody; MGC119523 antibody; MGC12866 antibody; MGC4816 antibody; Minichromosome maintenance 8 antibody; Minichromosome maintenance complex component 8 antibody; REC antibody
Similar products	minichromosome maintenance complex component 8
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	MCM8
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	C20orf154 antibody; dJ967N21.5 antibody; DNA helicase MCM8 antibody; DNA replication licensing factor MCM8 antibody; MCM8 antibody; MCM8_HUMAN antibody; MGC119522 antibody; MGC119523 antibody; MGC12866 antibody; MGC4816 antibody; Minichromosome maintenance 8 antibody; Minichromosome maintenance complex component 8 antibody; REC antibody
Immunogen Species	Human
Immunogen	Fusion protein of human MCM8
Dilution	ELISA:1:1000-1:2000 WB:1:200-1:1000
Background	The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Buffer	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method	Antigen affinity purification
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Fusion protein of Human MCM8
Clonality	Polyclonal

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