AKT1 Antibody

Polyclonal Antibody

AKT1

AKT 1 antibody, AKT antibody, AKT1 antibody, AKT1_HUMAN antibody, C AKT antibody, cAKT antibody, MGC99656 antibody, PKB alpha antibody, PKB antibody, PKB-ALPHA antibody, PRKBA antibody, Protein Kinase B Alpha antibody, Protein kinase B antibody, Proto-oncogene c-Akt antibody, RAC Alpha antibody, RAC antibody, Rac protein kinase alpha antibody, RAC Serine/Threonine Protein Kinase antibody, RAC-alpha serine/threonine-protein kinase antibody, RAC-PK-alpha antibody, v akt murine thymoma viral oncogene homolog 1 antibody, vAKT Murine Thymoma Viral Oncogene Homolog 1 antibody

Synthetic peptide of human pan-AKT

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.

Antigen Affinity Purified

Neuroscience

Synthetic peptide of Human pan-AKT