MMP13 Antibody

ArtNr	CSB-PA981877
Hersteller	Cusabio
Menge	100 ul
Kategorie	Neuroscience Neuroinflammation Antibodies Cell Biology Western Blot ELISA Cell Stainings ECM Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CLG 3 antibody,CLG3 antibody,Collagenase 3 antibody,Collagenase3 antibody,MANDP1 antibody,Matrix metallopeptidase 13 (collagenase 3) antibody,Matrix Metalloproteinase 13 antibody,Matrix metalloproteinase-13 antibody,MMP 13 antibody,MMP-13 antibody,Mmp13 antibody,MMP13_HUMAN antibody
Similar products	MMP13, Collagenase 3, CLG3, MANDP1, matrix metallopeptidase 13
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB; WB:1:500-1:1000
Manufacturer - Targets	MMP13
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	CLG 3 antibody, CLG3 antibody, Collagenase 3 antibody, Collagenase3 antibody, MANDP1 antibody, Matrix metallopeptidase 13 (collagenase 3) antibody, Matrix Metalloproteinase 13 antibody, Matrix metalloproteinase-13 antibody, MMP 13 antibody, MMP-13 antibody, Mmp13 antibody, MMP13_HUMAN antibody
Immunogen Species	Human
Immunogen	Peptide sequence around aa.355ca.359 (F-W-A-L-N) derived Human from MMP-13.
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:1000
Background	, Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion. , Guo A, et al. Proc Natl Acad Sci U S A 105, 692-7(2008) Rikova K, et al. Cell 131, 1190-203 (2007) ,
Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
General Research Areas	Cardiovascular
Initial Research Areas	Cardiovascular
Antigen Species	Human
Antigen	Peptide sequence around aa.355~359 (F-W-A-L-N) derived Human from MMP-13.
Clonality	Polyclonal

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Menge: 100 ul

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Lieferung vsl. bis 18.12.2025

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