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MMP13 Antibody

MMP13 Antibody

Item no.	CSB-PA981877
Manufacturer	Cusabio
Amount	100 ul
Category	Neuroscience Neuroinflammation Antibodies Cell Biology Western Blot ELISA Cell Stainings ECM Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CLG 3 antibody,CLG3 antibody,Collagenase 3 antibody,Collagenase3 antibody,MANDP1 antibody,Matrix metallopeptidase 13 (collagenase 3) antibody,Matrix Metalloproteinase 13 antibody,Matrix metalloproteinase-13 antibody,MMP 13 antibody,MMP-13 antibody,Mmp13 antibody,MMP13_HUMAN antibody
Similar products	MMP13, Collagenase 3, CLG3, MANDP1, matrix metallopeptidase 13
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB; WB:1:500-1:1000
Manufacturer - Targets	MMP13
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	CLG 3 antibody, CLG3 antibody, Collagenase 3 antibody, Collagenase3 antibody, MANDP1 antibody, Matrix metallopeptidase 13 (collagenase 3) antibody, Matrix Metalloproteinase 13 antibody, Matrix metalloproteinase-13 antibody, MMP 13 antibody, MMP-13 antibody, Mmp13 antibody, MMP13_HUMAN antibody
Immunogen Species	Human
Immunogen	Peptide sequence around aa.355ca.359 (F-W-A-L-N) derived Human from MMP-13.
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:1000
Background	, Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion. , Guo A, et al. Proc Natl Acad Sci U S A 105, 692-7(2008) Rikova K, et al. Cell 131, 1190-203 (2007) ,
Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
General Research Areas	Cardiovascular
Initial Research Areas	Cardiovascular
Antigen Species	Human
Antigen	Peptide sequence around aa.355~359 (F-W-A-L-N) derived Human from MMP-13.
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 12/18/2025

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