Vergleich

Recombinant Human Pleiotrophin protein(PTN) (Active)

ArtNr CSB-AP002931HU-100
Hersteller Cusabio
Menge 100 ug
Quantity options 1 mg 100 ug 20 ug 250 ug 5 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Konjugat/Tag Tag Free
Purity >96% as determined by SDS­PAGE and HPLC.
Sequence GKKEKPEKKV KKSDCGEWQW SVCVPTSGDC GL GTREGTRT GAECKQTMKT QRCKIPCNWK KQFG AECKYQ FQAWGECDLN TALKTRTGSL KRALHN AECQ KTVTISKPCG KLTKPKPQAE SKKKKKEG KK QEKMLD
Protein Familie Pleiotrophin family
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias PTN,HBBM,Heparin-binding growth factor 8,HBGF-8,Heparin-binding growth-associated molecule
Lieferbar
Manufacturer - Category
Cytokine / Growth Factor
Molecular Weight
15.3 kDa
Buffer
0.2 m filtered PBS, pH 7.4 , lyophilized
General Research Areas
Immunology
Relevance
Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation. {ECO:0000269|PubMed:11278720, ECO:0000269|PubMed:1768439}.
Expression Region
33-168aa
Function
Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells
Subcellular Location
Secreted
Tissue Specificity
Osteoblast and brain.
Gene Names
PTN, HBNF1, NEGF1
Endotoxin
Less than 1.0 EU/ug as determined by LAL method.
Biological activity
Fully biologically active when compared to standard. The biological activity was measured by its ability to enhance neurite outgrowth of E16­E18 rat embryonic cortical neurons, when neurons were plated on 96 well culture plates that had been pre­coated with 100 ul/well of a solution of 5­10 ug/ml rHuPTN.
Manufacturer - Format
Lyophilized powder
Uniprot Entry Name
PTN_HUMAN
Protein Description
Full Length of Mature Protein
PubMed ID
1701634; 2270483; 1768439; 1457401; 8484754; 9299545; 14702039; 12690205; 15489334; 2388713; 1733956; 8241100; 8484780; 11278720; 20873783

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen