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Recombinant Human Casein kinase I isoform alpha(CSNK1A1)

ArtNr CSB-EP006065HU-500
Hersteller Cusabio
Menge 500 ug
Quantity options 1 mg 10 ug 100 ug 20 ug 200 ug 50 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid or Lyophilized powder
Specific against other
Host E.coli
Konjugat/Tag HIS
Purity Greater than 90% as determined by SDS-PAGE.
Sequence ASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAIN ITNGEEVAVKLESQKARHPQLLYESKLYKILQGGV GIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSR RFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDN FLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYR EDKNLTGTARYASINAHLGIEQSRRDDMESLGYVL MYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVE VLC
Protein Familie Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily
Citations Cloning and chromosomal localization of the gene coding for human protein kinase CK1.Tapia C., Featherstone T., Gomez C., Taillon-Miller P., Allende C.C., Allende J.E.FEBS Lett. 349:307-312(1994)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CK1
Lieferbar
Manufacturer - Conjugate / Tag
N-terminal 6xHis-tagged
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Molecular Weight
42.8 kDa
General Research Areas
Cell Cycle
Relevance
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis.
Expression Region
2-337aa
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis
Subcellular Location
Cytoplasm, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Chromosome, centromere, kinetochore, Nucleus speckle, Cytoplasm, cytoskeleton, cilium basal body
Paythway
Hedgehogsignalingpathway
Gene Names
CSNK1A1
Sequence Info
Full Length of Mature Protein
Organism
Homo sapiens (Human)
Storage Buffer
Tris-based buffer, 50% glycerol

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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Lieferung vsl. bis 28.08.2025 

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