Vergleich

Recombinant Human Vitamin K-dependent protein S(PROS1)

Hersteller Cusabio
Kategorie
Typ Proteins Recombinant
Specific against other
Format Liquid or Lyophilized powder
Menge 500ug
Host E.coli
ArtNr CSB-EP018754HU-500
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Research areas
Cardiovascular
Target / Protein
PROS1
Biologically active
Not Test
Expression system
E.coli
Species of origin
Homo sapiens (Human)
Uniprot ID
P07225
AA Sequence
ANSLLEETKQGNLERECIEELCNKEEAREVFENDP ETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLR SCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCK PGWQGEKCEFDINECKDPSNINGGCSQICDNTPGS YHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAV CKNIPGDFECECPEGYRYNLKSKSCEDIDECSENM CAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVS VCLPLNLDTKYELLYLAEQFAGVVLYLKFRLPEIS RFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRG GKIEVQLKNEHTSKITTGGDVINNGLWNMVSVEEL EHSISIKIAKEAVMDINKPGPLFKPENGLLETKVY FAGFPRKVESELIKPINPRLDGCIRSWNLMKQGAS GIKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHID YNNVSSAEGWHVNVTLNIRPSTGTGVMLALVSGNN TVPFAVSLVDSTSEKSQDILLSVENTVIYRIQALS LCSDQQSHLEFRVNRNNLELSTPLKIETISHEDLQ RQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFY NGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVWK KTKNS
Tag Info
N-terminal 6xHis-SUMO-tagged
Expression Region
42-676aa
Protein length
Full Length of Mature Protein
MW
86.6 kDa
Relevance
Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
References
Human protein S cDNA encodes Phe-16 and Tyr 222 in consensus sequences for the post-translational processing.Ploos van Amstel H.K., van der Zanden A.L., Reitsma P.H., Bertina R.M.FEBS Lett. 222:186-190(1987)
Purity
Greater than 90% as determined by SDS-PAGE.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
Involvement in disease
Thrombophilia due to protein S deficiency, autosomal dominant (THPH5); Thrombophilia due to protein S deficiency, autosomal recessive (THPH6)
Subcellular Location
Secreted
Tissue Specificity
Plasma.
Paythway
Complementandcoagulationcascades
Tag Information
N-terminal 6xHis-SUMO-tagged

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500ug
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen