Hersteller |
Cusabio
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Format |
Liquid or Lyophilized powder |
Menge |
200ug |
Host |
E.coli |
ArtNr |
CSB-EP019216HU-200 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Research Topic |
Transport |
Uniprot ID |
P20340 |
Gene Names |
RAB6A |
Organism |
Homo sapiens (Human) |
AA Sequence |
STGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYD SFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAG QERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTK WIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEG ERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPG MESTQDRSREDMIDIKLEKPQEQPVSEGGCSC |
Expression Region |
2-208aa |
Sequence Info |
Full Length of Mature Protein |
Source |
E.coli |
Tag Info |
N-terminal 6xHis-SUMO-tagged |
MW |
39.5 kDa |
Relevance |
Protein transport. Regulator of mbrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity. |
Reference |
The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.Zahraoui A., Touchot N., Chardin P., Tavitian A.J. Biol. Chem. 264:12394-12401(1989) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity. Involved in COPI-independent retrograde transport from the Golgi to the ER |
Subcellular Location |
Golgi apparatus membrane, Lipid-anchor |
Protein Families |
Small GTPase superfamily, Rab family |
Tissue Specificity |
Ubiquitous. |
Tag Information |
N-terminal 6xHis-SUMO-tagged |
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