Manufacturer |
Cusabio
|
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
Format |
Liquid or Lyophilized powder |
Amount |
200ug |
Host |
E.coli |
Item no. |
CSB-EP019216HU-200 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Available |
|
Research Topic |
Transport |
Uniprot ID |
P20340 |
Gene Names |
RAB6A |
Organism |
Homo sapiens (Human) |
AA Sequence |
STGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYD SFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAG QERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTK WIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEG ERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPG MESTQDRSREDMIDIKLEKPQEQPVSEGGCSC |
Expression Region |
2-208aa |
Sequence Info |
Full Length of Mature Protein |
Source |
E.coli |
Tag Info |
N-terminal 6xHis-SUMO-tagged |
MW |
39.5 kDa |
Relevance |
Protein transport. Regulator of mbrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity. |
Reference |
The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.Zahraoui A., Touchot N., Chardin P., Tavitian A.J. Biol. Chem. 264:12394-12401(1989) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity. Involved in COPI-independent retrograde transport from the Golgi to the ER |
Subcellular Location |
Golgi apparatus membrane, Lipid-anchor |
Protein Families |
Small GTPase superfamily, Rab family |
Tissue Specificity |
Ubiquitous. |
Tag Information |
N-terminal 6xHis-SUMO-tagged |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.