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Recombinant Human Oncostatin-M protein(OSM) (Active)

Recombinant Human Oncostatin-M protein(OSM) (Active)

ArtNr	CSB-AP002231HU-10
Hersteller	Cusabio
Menge	10 ug
Quantity options	1 mg 10 ug 100 ug 2 ug 250 ug 500 ug
Kategorie	Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Peptides & Proteins Recombinant Proteins Glial Cell Markers
Typ	Proteins Recombinant
Format	Solid
Specific against	other
Host	E.coli
Konjugat/Tag	Tag Free
Purity	>97% as determined by SDS-PAGE and HPLC.
Sequence	AAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LD PYIRIQGL DVPKLREHCR ERPGAFPSEE TLRG LGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQ DLER SGLNIEDLEK LQMARPNILG LRNNIYCM AQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES P NRSR
Protein Familie	LIF/OSM family
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	OSM,
Lieferbar
Manufacturer - Category	Cytokine / Growth Factor
Molecular Weight	22.0 kDa
Buffer	0.2 um filtered PBS, pH 7.4 , lyophilized
General Research Areas	Immunology
Relevance	Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity). {ECO:0000250}.
Expression Region	26-220aa
Function	Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity).
Subcellular Location	Secreted
Pathway	Jak-STATsignalingpathway
Gene Names	OSM
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Biological activity	Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 2 ng/ml, corresponding to a specific activity of ? 5.0 x 105 IU/mg.
Manufacturer - Format	Lyophilized powder
Uniprot Entry Name	ONCM_HUMAN
Protein Description	Partial
PubMed ID	2779549; 15461802; 10591208; 15489334; 3540948; 1542792; 2325640; 2026606; 1717982; 1542793; 8999038; 10997905

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CSB-AP002231HU-10-datasheet.pdf

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Menge: 10 ug

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Lieferung vsl. bis 04.12.2025

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