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Recombinant Apis mellifera Major royal jelly protein 1(MRJP1)

ArtNr CSB-BP522725DNK-500
Hersteller Cusabio
Menge 500 ug
Quantity options 1 mg 10 ug 100 ug 20 ug 50 ug 500 ug
Kategorie
Typ Proteins Recombinant
Specific against other
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity Greater than 85% as determined by SDS-PAGE.
Sequence NILRGESLNKSLPILHEWKFFDYDFGSDERRQDAI LSGEYDYKNNYPSDIDQWHDKIFVTMLRYNGVPSS LNVISKKVGDGGPLLQPYPDWSFAKYDDCSGIVSA SKLAIDKCDRLWVLDSGLVNNTQPMCSPKLLTFDL TTSQLLKQVEIPHDVAVNATTGKGRLSSLAVQSLD CNTNSDTMVYIADEKGEGLIVYHNSDDSFHRLTSN TFDYDPKFTKMTIDGESYTAQDGISGMALSPMTNN LYY
Protein Familie Major royal jelly protein family
Citations "Change in the mode of gene expression of the hypopharyngeal gland cells with an age-dependent role change of the worker honeybee Apis mellifera L."
Ohashi K., Natori S., Kubo T.
Eur. J. Biochem. 249:797-802(1997)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias 56-KDA protein 4
Lieferbar
Manufacturer - Targets
MRJP1
Manufacturer - Conjugate / Tag
N-terminal 10xHis-tagged
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Molecular Weight
49.4 kDa
Relevance
Major royal jelly protein 1: induces the differentiation of honeybee larvae into queens through an Egfr-mediated signaling pathway. Promotes body size increase by activating p70 S6 kinase, stimulates ovary development by augmenting the titer of vitellogenin (Vg) and juvenile hormone, and reduces developmental time by increasing the activity of mitogen-activated protein kinase and inducing the 20-hydroxyecdysone protein (20E). Most abundant protein found in the royal jelly which is the food of the queen honey bee larva. The royal jelly determines the development of the young larvae and is responsible for the high reproductive ability of the honeybee queen.
Jellein-1: has antibacterial activity against the Gram-positive bacteria S.aureus ATCC 6535, S.saprophyticus and B.subtilis CCT2471, and the Gram-negative bacteria E.coli CCT1371, E.cloacae ATCC 23355, K.pneumoniae ATCC 13883 and P.aeruginosa ATCC 27853, and antifungal activity against C.albicans. Lack cytolytic activity and does not induce rat peritoneal mast cell degranulation.
Jellein-2: has antibacterial activity against the Gram-positive bacteria S.aureus ATCC 6535, S.saprophyticus and B.subtilis CCT2471, and the Gram-negative bacteria E.coli CCT1371, E.cloacae ATCC 23355, K.pneumoniae ATCC 13883 and P.aeruginosa ATCC 27853, and antifungal activity against C.albicans. Lack cytolytic activity and does not induce rat peritoneal mast cell degranulation.
Jellein-4: lacks antibacterial and antifungal activity. Lacks cytolytic activity and does not induce rat peritoneal mast cell degranulation.
Expression Region
20-432aa
Protein Length
Full Length of Mature Protein
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Major royal jelly protein 1
Subcellular Location
Secreted
Tissue Specificity
Found in the hypopharyngeal glands of the worker honeybee.
Biological activity
Not Test
Manufacturer - Format
Liquid or Lyophilized powder

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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