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Recombinant Human Aflatoxin B1 aldehyde reductase member 3(AKR7A3)

ArtNr CSB-EP001551HU-200
Hersteller Cusabio
Menge 200 ug
Quantity options 1 mg 10 ug 100 ug 20 ug 200 ug 50 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid or Lyophilized powder
Specific against other
Host E.coli
Konjugat/Tag GST
Purity Greater than 90% as determined by SDS-PAGE.
Sequence MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAF LERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDC RVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCP RVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVEL GLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAI TRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYK YEDKDGKQPVGRFFGNTWAEMYRNRYWKEHHFEGI ALV
Protein Familie Aldo/keto reductase family, Aldo/keto reductase 2 subfamily
Citations "cDNA cloning, expression and activity of a second human aflatoxin B1-metabolizing member of the aldo-keto reductase superfamily, AKR7A3."
Knight L.P., Primiano T., Groopman J.D., Kensler T.W., Sutter T.R.
Carcinogenesis 20:1215-1223(1999)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias AFB1 aldehyde reductase 2
Lieferbar
Manufacturer - Conjugate / Tag
N-terminal GST-tagged
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Molecular Weight
64.2 kDa
General Research Areas
Signal Transduction
Relevance
Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
Expression Region
1-331aa
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
Subcellular Location
Cytoplasm
Tissue Specificity
Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium.
Gene Names
AKR7A3
Sequence Info
Full Length of BC025709
Organism
Homo sapiens (Human)
Storage Buffer
Tris-based buffer, 50% glycerol

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 ug
Lieferbar: In stock
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