Vergleich

Recombinant Mouse 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Cyp27b1)

ArtNr CSB-EP006406MO-50
Hersteller Cusabio
Menge 50 ug
Quantity options 1 mg 10 ug 100 ug 20 ug 200 ug 50 ug 500 ug
Kategorie
Typ Proteins Recombinant
Specific against other
Konjugat/Tag HIS
Purity Greater than 90% as determined by SDS-PAGE.
Sequence MTQAVKLASRVFHRIHLPLQLDASLGSRGSESVLR SLSDIPGPSTLSFLAELFCKGGLSRLHELQVHGAA RYGPIWSGSFGTLRTVYVADPTLVEQLLRQESHCP ERCSFSSWAEHRRRHQRACGLLTADGEEWQRLRSL LAPLLLRPQAAAGYAGTLDNVVRDLVRRLRRQRGR GSGLPGLVLDVAGEFYKFGLESIGAVLLGSRLGCL EAEVPPDTETFIHAVGSVFVSTLLTMAMPNWLHHL IPG
Protein Familie Cytochrome P450 family
Citations "25-hydroxyvitamin D 1alpha-hydroxylase: structure of the mouse gene, chromosomal assignment, and developmental expression."
Panda D.K., Al-Kawas S., Seldin M.F., Hendy G.N., Goltzman D.
J. Bone Miner. Res. 16:46-56(2001)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias 25-OHD-1 alpha-hydroxylase,25-hydroxyvitamin D(3) 1-alpha-hydroxylase
Lieferbar
Manufacturer - Conjugate / Tag
N-terminal 6xHis-tagged
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Molecular Weight
60.2 kDa
Buffer
Tris-based buffer, 50% glycerol
Relevance
Catalyzes the conversion of 25-hydroxyvitamin D3 (25(OH)D3) to 1-alpha, 25-dihydroxyvitamin D3 (1alpha, 25(OH)2D3), and of 24, 25-dihydroxyvitamin D3 (24, 25(OH)2D3) to 1-alpha, 24, 25-trihydroxyvitamin D3 (1alpha, 24, 25(OH)3D3). Is also active with 25-hydroxy-24-oxo-vitamin D3. Plays an important role in normal bone growth, calcium metabolism, and tissue differentiation.
Expression Region
1-507aa
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Catalyzes the conversion of 25-hydroxyvitamin D3 (25(OH)D3) to 1-alpha, 25-dihydroxyvitamin D3 (1alpha, 25(OH)(2)D3), and of 24, 25-dihydroxyvitamin D3 (24, 25(OH)(2)D3) to 1-alpha, 24, 25-trihydroxyvitamin D3 (1alpha, 24, 25(OH)(3)D3). Is also active with 25-hydroxy-24-oxo-vitamin D3. Plays an important role in normal bone growth, calcium metabolism, and tissue differentiation.
Subcellular Location
Mitochondrion membrane
Tissue Specificity
Kidney.
Gene Names
Cyp27b1
Sequence Info
Full Length
Organism
Mus musculus (Mouse)
Manufacturer - Format
Liquid or Lyophilized powder

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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Lieferung vsl. bis 23.10.2025 

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