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Recombinant Mouse Glucagon-like peptide 1 receptor(Glp1r),partial

Recombinant Mouse Glucagon-like peptide 1 receptor(Glp1r),partial

Hersteller	Cusabio
Kategorie	Metabolism Diabetes Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	other
Format	Liquid or Lyophilized powder
Menge	50ug
Host	E.coli
ArtNr	CSB-EP009514MO1-50
eClass 6.1	34160400
eClass 9.0	42020190
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Research areas	Neuroscience
Target / Protein	Glp1r
Biologically active	Not Test
Expression system	E.coli
Species of origin	Mus musculus (Mouse)
Uniprot ID	O35659
AA Sequence	GPRPQGTTVSLSETVQKWREYRRQCQRFLTEAPLL ATGLFCNRTFDDYACWPDGPPGSFVNVSCPWYLPW ASSVLQGHVYRFCTAEGLWLHKDNSSLPWRDLSEC EESKRGERNFPEEQLLSLY
Tag Info	N-terminal 6xHis-SUMO-tagged
Expression Region	22-145aa
Protein length	Partial
MW	30.4 kDa
Alternative Name(s)	Short name: GLP-1 receptor Short name: GLP-1-R Short name: GLP-1R
Relevance	This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
References	"Mouse pancreatic beta-cells exhibit preserved glucose competence after disruption of the glucagon-like peptide-1 receptor gene."Flamez D., van Breusegem A., Scrocchi L.A., Quartier E., Pipeleers D., Drucker D.J., Schuit F.Diabetes 47:646-652(1998)
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1)
Subcellular Location	Cell membrane, Multi-pass membrane protein
Protein Families	G-protein coupled receptor 2 family
Tissue Specificity	Detected in pancreatic islets (at protein level). Detected in pancreatic islets and lungs.
Tag Information	N-terminal 6xHis-SUMO-tagged

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