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Recombinant Mouse Glucagon-like peptide 1 receptor(Glp1r),partial

Recombinant Mouse Glucagon-like peptide 1 receptor(Glp1r),partial

Manufacturer	Cusabio
Category	Metabolism Diabetes Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Format	Liquid or Lyophilized powder
Amount	50ug
Host	E.coli
Item no.	CSB-EP009514MO1-50
eClass 6.1	34160400
eClass 9.0	42020190
Available
Research areas	Neuroscience
Target / Protein	Glp1r
Biologically active	Not Test
Expression system	E.coli
Species of origin	Mus musculus (Mouse)
Uniprot ID	O35659
AA Sequence	GPRPQGTTVSLSETVQKWREYRRQCQRFLTEAPLL ATGLFCNRTFDDYACWPDGPPGSFVNVSCPWYLPW ASSVLQGHVYRFCTAEGLWLHKDNSSLPWRDLSEC EESKRGERNFPEEQLLSLY
Tag Info	N-terminal 6xHis-SUMO-tagged
Expression Region	22-145aa
Protein length	Partial
MW	30.4 kDa
Alternative Name(s)	Short name: GLP-1 receptor Short name: GLP-1-R Short name: GLP-1R
Relevance	This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
References	"Mouse pancreatic beta-cells exhibit preserved glucose competence after disruption of the glucagon-like peptide-1 receptor gene."Flamez D., van Breusegem A., Scrocchi L.A., Quartier E., Pipeleers D., Drucker D.J., Schuit F.Diabetes 47:646-652(1998)
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1)
Subcellular Location	Cell membrane, Multi-pass membrane protein
Protein Families	G-protein coupled receptor 2 family
Tissue Specificity	Detected in pancreatic islets (at protein level). Detected in pancreatic islets and lungs.
Tag Information	N-terminal 6xHis-SUMO-tagged

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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