Hersteller |
Cusabio
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Menge |
10ug |
Host |
E.coli |
ArtNr |
CSB-EP009870HU-10 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Research Topic |
Signal Transduction |
Uniprot ID |
O75715 |
Gene Names |
GPX5 |
Organism |
Homo sapiens (Human) |
AA Sequence |
MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKD EKGTIYDYEAIALNKNEYVSFKQYVGKHILFVNVA TYCGLTAQYPGMSVQGEDLYLVSSFLRKGM |
Expression Region |
1-100aa |
Sequence Info |
Full Length of Isoform 2 |
Source |
E.coli |
Tag Info |
N-terminal 6xHis-Trx-tagged |
MW |
28.4 kDa |
Alternative Name(s) |
Epididymis-specific glutathione peroxidase-like protein |
Relevance |
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. |
Reference |
"The majority of human glutathione peroxidase type 5 (GPX5) transcripts are incorrectly spliced: implications for the role of GPX5 in the male reproductive tract." Hall L., Williams K., Perry A.C.F., Frayne J., Jury J.A. Biochem. J. 333:5-9(1998) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. |
Subcellular Location |
Secreted |
Protein Families |
Glutathione peroxidase family |
Tissue Specificity |
Epididymis. |
Paythway |
Th17celldifferentiation |
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