Hersteller |
Cusabio
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Format |
Liquid or Lyophilized powder |
Menge |
50ug |
Host |
E.coli |
ArtNr |
CSB-EP015471HU-50 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Research areas |
Signal Transduction |
Target / Protein |
NAT2 |
Biologically active |
Not Test |
Expression system |
E.coli |
Species of origin |
Homo sapiens (Human) |
Uniprot ID |
P11245 |
AA Sequence |
MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAV PFENLNMHCGQAMELGLEAIFDHIVRRNRGGWCLQ VNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGM VHLLLQVTIDGRNYIVDAGSGSSSQMWQPLELISG KDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEF LNSHLLPKKKHQKIYLFTLEPRTIEDFESMNTYLQ TSPTSSFITTSFCSLQTPEGVYCLVGFILTYRKFN YKDNTDLVEFKTLTEEEVEEVLKNIFKISLGRNLV PKPGDGSLTI |
Tag Info |
N-terminal 6xHis-SUMO-tagged |
Expression Region |
1-290aa |
Protein length |
Full Length |
MW |
49.5 kDa |
Alternative Name(s) |
Arylamide acetylase 2 N-acetyltransferase type 2 Short name: NAT-2 Polymorphic arylamine N-acetyltransferase Short name: PNAT |
Relevance |
Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. |
References |
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."The MGC Project Team Genome Res. 14:2121-2127(2004) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. |
Subcellular Location |
Cytoplasm |
Protein Families |
Arylamine N-acetyltransferase family |
Tag Information |
N-terminal 6xHis-SUMO-tagged |
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