Hersteller |
Cusabio
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Format |
Liquid or Lyophilized powder |
Menge |
500ug |
Host |
E.coli |
ArtNr |
CSB-EP017946HU-500 |
Konjugat/Tag |
GST |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Research Topic |
Signal Transduction |
Uniprot ID |
O14832 |
Gene Names |
PHYH |
Organism |
Homo sapiens (Human) |
AA Sequence |
SGTISSASFHPQQFQYTLDNNVLTLEQRKFYEENG FLVIKNLVPDADIQRFRNEFEKICRKEVKPLGLTV MRDVTISKSEYAPSEKMITKVQDFQEDKELFRYCT LPEILKYVECFTGPNIMAMHTMLINKPPDSGKKTS RHPLHQDLHYFPFRPSDLIVCAWTAMEHISRNNGC LVVLPGTHKGSLKPHDYPKWEGGVNKMFHGIQDYE ENKARVHLVMEKGDTVFFHPLLIHGSGQNKTQGFR KAISCHFASADCHYIDVKGTSQENIEKEVVGIAHK FFGAENSVNLKDIWMFRARLVKGERTNL |
Expression Region |
1-338aa |
Sequence Info |
Full Length |
Source |
E.coli |
Tag Info |
N-terminal GST-tagged |
MW |
62.4 kDa |
Alternative Name(s) |
Phytanic acid oxidase Phytanoyl-CoA alpha-hydroxylase |
Relevance |
Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. |
Reference |
"Identification of PAHX, a Refsum disease gene." Mihalik S.J., Morrell J.C., Kim D., Sachsteder K.A., Watkins P.A., Gould S.J. Nat. Genet. 17:185-189(1997) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. |
Involvement in disease |
Refsum disease (RD) |
Subcellular Location |
Peroxisome |
Protein Families |
PhyH family |
Tissue Specificity |
Expressed in liver, kidney, and T-cells, but not in spleen, brain, heart, lung and skeletal muscle. |
Tag Information |
N-terminal GST-tagged |
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