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Recombinant Human Mitochondrial carnitine/acylcarnitine carrier protein(SLC25A20)

Hersteller Cusabio
Kategorie
Typ Proteins Recombinant
Specific against other
Format Liquid or Lyophilized powder
Menge 10ug
Host E.coli
ArtNr CSB-EP021488HU-10
Konjugat/Tag GST
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Research Topic
Signal Transduction
Uniprot ID
O43772
Gene Names
SLC25A20
Organism
Homo sapiens (Human)
AA Sequence
MADQPKPISPLKNLLAGGFGGVCLVFVGHPLDTVK VRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITG LYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPE DVLSYPQLFAAGMLSGVFTTGIMTPGERIKCLLQI QASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLT LMRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAP RILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKY PNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPAN AACFLGFEVAMKFLNWATPNL
Expression Region
1-301aa
Sequence Info
Full Length
Source
E.coli
Tag Info
N-terminal GST-tagged
MW
59.9 kDa
Alternative Name(s)
Carnitine/acylcarnitine translocase
Relevance
Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway.
Reference
"The structure and organization of the human carnitine/acylcarnitine translocase (CACT) gene."
Iacobazzi V., Naglieri M.A., Stanley C.A., Wanders R.J.A., Palmieri F.
Biochem. Biophys. Res. Commun. 252:770-774(1998)
Purity
Greater than 90% as determined by SDS-PAGE.
Storage Buffer
Tris-based buffer, 50% glycerol
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway.
Involvement in disease
Carnitine-acylcarnitine translocase deficiency (CACTD)
Subcellular Location
Mitochondrion inner membrane, Multi-pass membrane protein
Protein Families
Mitochondrial carrier (TC 2.A.29) family
Tag Information
N-terminal GST-tagged

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10ug
Lieferbar: In stock
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