Hersteller |
Cusabio
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Format |
Liquid or Lyophilized powder |
Menge |
50ug |
Host |
Mammalian cells |
ArtNr |
CSB-MP012911HU-50 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Research Topic |
Cardiovascular |
Uniprot ID |
P22888 |
Gene Names |
LHCGR |
Organism |
Homo sapiens (Human) |
AA Sequence |
EALCPEPCNCVPDGALRCPGPTAGLTRLSLAYLPV KVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDN LLNLSEILIQNTKNLRYIEPGAFINLPRLKYLSIC NTGIRKFPDVTKVFSSESNFILEICDNLHITTIPG NAFQGMNNESVTLKLYGNGFEEVQSHAFNGTTLTS LELKENVHLEKMHNGAFRGATGPKTLDISSTKLQA LPSYGLESIQRLIATSSYSLKKLPSRETFVNLLEA TLTYPSHCCAFRNLPTKEQNFSHSISENFSKQCES TVRKVNNKTLYSSMLAESELSGWDYEYGFCLPKTP RCAPEPDAFNPCEDIMGYDFL |
Expression Region |
27-362aa |
Sequence Info |
Full Length of Mature Protein |
Source |
Mammalian cell |
Tag Info |
N-terminal 6xHis-tagged |
MW |
41.4 kDa |
Alternative Name(s) |
Luteinizing hormone receptor Short name: LHR Short name: LSH-R |
Relevance |
Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Reference |
"Cloning and sequencing of human LH/hCG receptor cDNA."Minegish T., Nakamura K., Takakura Y., Miyamoto K., Hasegawa Y., Ibuki Y., Igarashi M.Biochem. Biophys. Res. Commun. 172:1049-1054(1990) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Receptor for lutropin-choriogonadotropic hormone |
Involvement in disease |
Familial male precocious puberty (FMPP); Luteinizing hormone resistance (LHR) |
Subcellular Location |
Cell membrane, Multi-pass membrane protein |
Protein Families |
G-protein coupled receptor 1 family, FSH/LSH/TSH subfamily |
Tissue Specificity |
Gonadal and thyroid cells. |
Paythway |
Calciumsignalingpathway |
Tag Information |
N-terminal 6xHis-tagged |
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