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Recombinant Pig Complement C5a anaphylatoxin(C5)

Recombinant Pig Complement C5a anaphylatoxin(C5)

ArtNr	CSB-YP003995PI-200
Hersteller	Cusabio
Menge	200 ug
Quantity options	1 mg 10 ug 100 ug 200 ug 20 ug 50 ug 500 ug
Kategorie	Oncology Food Safety Histamines Neuroscience Neuroinflammation Peptides & Proteins Recombinant Proteins By Organ Skin Cancer
Typ	Proteins Recombinant
Specific against	other
Host	Yeast
Konjugat/Tag	HIS
Purity	Greater than 90% as determined by SDS-PAGE.
Sequence	MLQKKIEEEAAKYKYAMLKKCCYDGAYRNDDETCE ERAARIKIGPKCVKAFKDCCYIANQVRAEQSHKNI QLGR
Citations	Three-dimensional structure of porcine C5adesArg from 1H nuclear magnetic resonance data.Williamson M.P., Madison V.S.Biochemistry 29:2895-2905(1990)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
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Manufacturer - Conjugate / Tag	N-terminal 6xHis-tagged
Storage Conditions	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Molecular Weight	10.6 kDa
Relevance	Derived from proteolytic degradation of complent C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.
Expression Region	1-74aa
Protein Length	Full Length
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.
Subcellular Location	Secreted
Biological activity	Not Test
Manufacturer - Format	Liquid or Lyophilized powder

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CSB-YP003995PI-200-datasheet.pdf

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Menge: 200 ug

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Lieferung vsl. bis 30.10.2025

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