Hersteller |
Cusabio
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Format |
Liquid or Lyophilized powder |
Menge |
50ug |
Host |
Yeast |
ArtNr |
CSB-YP356570DLU-50 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Research Topic |
Others |
Uniprot ID |
P05623 |
Gene Names |
SP |
Organism |
Drosophila melanogaster (Fruit fly) |
AA Sequence |
WEWPWNRKPTKFPIPSPNPRDKWCRLNLGPAWGGR |
Expression Region |
20-55aa |
Sequence Info |
Full Length of Mature Protein |
Source |
Yeast |
Tag Info |
Tag-Free |
MW |
4.3 kDa |
Alternative Name(s) |
Paragonial peptide B Sex peptide Short name: SP |
Relevance |
Male seminal protein which triggers short- and long-term post-mating behavioral responses (PMR) in female Drosophila (PubMed:3135120, PubMed:19249273, PubMed:20308537, PubMed:19793753, PubMed:15694303, PubMed:24089336). Binds initially to sperm where it is later cleaved to release an active peptide within the female reproductive tract. Signals via the sex peptide receptor (SPR) in female flies; may also act via other receptors (PubMed:20458515, PubMed:20308537, PubMed:24089336). Moderates the activity of distinct neuronal circuitries in the female genital tract to promote specific PMRs including: enhanced ovulation, increased egg laying rate, increased feeding/foraging rate, induced antimicrobial peptide synthesis, reduced mating receptivity, reduced day-time sleep and reduced lifespan in multiple mated females (PubMed:3135120, PubMed:15694303, PubMed:19249273, PubMed:19793753, PubMed:24089336). |
Reference |
"Population genetics of accessory gland proteins and sexual behavior in Drosophila melanogaster populations from Evolution Canyon."Panhuis T.M., Swanson W.J., Nunney L.Evolution 57:2785-2791(2003) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Male seminal protein which triggers short- and long-term post-mating behavioral responses (PMR) in female Drosophila |
Subcellular Location |
Secreted |
Protein Families |
Drosophila sex peptide family |
Tissue Specificity |
Main cells of the accessory glands of males (paragonial gland). |
Tag Information |
Tag-Free |
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