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Recombinant Fruit fly Accessory gland-specific peptide 70A(SP)

Hersteller Cusabio
Kategorie
Typ Proteins Recombinant
Specific against other
Format Liquid or Lyophilized powder
Menge 50ug
Host Yeast
ArtNr CSB-YP356570DLU-50
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Research Topic
Others
Uniprot ID
P05623
Gene Names
SP
Organism
Drosophila melanogaster (Fruit fly)
AA Sequence
WEWPWNRKPTKFPIPSPNPRDKWCRLNLGPAWGGR
Expression Region
20-55aa
Sequence Info
Full Length of Mature Protein
Source
Yeast
Tag Info
Tag-Free
MW
4.3 kDa
Alternative Name(s)
Paragonial peptide B
Sex peptide
Short name:
SP
Relevance
Male seminal protein which triggers short- and long-term post-mating behavioral responses (PMR) in female Drosophila (PubMed:3135120, PubMed:19249273, PubMed:20308537, PubMed:19793753, PubMed:15694303, PubMed:24089336). Binds initially to sperm where it is later cleaved to release an active peptide within the female reproductive tract. Signals via the sex peptide receptor (SPR) in female flies; may also act via other receptors (PubMed:20458515, PubMed:20308537, PubMed:24089336). Moderates the activity of distinct neuronal circuitries in the female genital tract to promote specific PMRs including: enhanced ovulation, increased egg laying rate, increased feeding/foraging rate, induced antimicrobial peptide synthesis, reduced mating receptivity, reduced day-time sleep and reduced lifespan in multiple mated females (PubMed:3135120, PubMed:15694303, PubMed:19249273, PubMed:19793753, PubMed:24089336).
Reference
"Population genetics of accessory gland proteins and sexual behavior in Drosophila melanogaster populations from Evolution Canyon."Panhuis T.M., Swanson W.J., Nunney L.Evolution 57:2785-2791(2003)
Purity
Greater than 90% as determined by SDS-PAGE.
Storage Buffer
Tris-based buffer, 50% glycerol
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Male seminal protein which triggers short- and long-term post-mating behavioral responses (PMR) in female Drosophila
Subcellular Location
Secreted
Protein Families
Drosophila sex peptide family
Tissue Specificity
Main cells of the accessory glands of males (paragonial gland).
Tag Information
Tag-Free

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50ug
Lieferbar: In stock
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