Manufacturer |
Cusabio
|
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
Format |
Liquid or Lyophilized powder |
Amount |
50ug |
Host |
Yeast |
Item no. |
CSB-YP356570DLU-50 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Available |
|
Research Topic |
Others |
Uniprot ID |
P05623 |
Gene Names |
SP |
Organism |
Drosophila melanogaster (Fruit fly) |
AA Sequence |
WEWPWNRKPTKFPIPSPNPRDKWCRLNLGPAWGGR |
Expression Region |
20-55aa |
Sequence Info |
Full Length of Mature Protein |
Source |
Yeast |
Tag Info |
Tag-Free |
MW |
4.3 kDa |
Alternative Name(s) |
Paragonial peptide B Sex peptide Short name: SP |
Relevance |
Male seminal protein which triggers short- and long-term post-mating behavioral responses (PMR) in female Drosophila (PubMed:3135120, PubMed:19249273, PubMed:20308537, PubMed:19793753, PubMed:15694303, PubMed:24089336). Binds initially to sperm where it is later cleaved to release an active peptide within the female reproductive tract. Signals via the sex peptide receptor (SPR) in female flies; may also act via other receptors (PubMed:20458515, PubMed:20308537, PubMed:24089336). Moderates the activity of distinct neuronal circuitries in the female genital tract to promote specific PMRs including: enhanced ovulation, increased egg laying rate, increased feeding/foraging rate, induced antimicrobial peptide synthesis, reduced mating receptivity, reduced day-time sleep and reduced lifespan in multiple mated females (PubMed:3135120, PubMed:15694303, PubMed:19249273, PubMed:19793753, PubMed:24089336). |
Reference |
"Population genetics of accessory gland proteins and sexual behavior in Drosophila melanogaster populations from Evolution Canyon."Panhuis T.M., Swanson W.J., Nunney L.Evolution 57:2785-2791(2003) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Male seminal protein which triggers short- and long-term post-mating behavioral responses (PMR) in female Drosophila |
Subcellular Location |
Secreted |
Protein Families |
Drosophila sex peptide family |
Tissue Specificity |
Main cells of the accessory glands of males (paragonial gland). |
Tag Information |
Tag-Free |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.