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Human DLL4 Protein, Fc Tag, low endotoxin (MALS & SPR verified)

Human DLL4 Protein, Fc Tag, low endotoxin (MALS & SPR verified)

ArtNr	DL4-H5259-500ug
Hersteller	ACROBiosystems
Menge	500 ug
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Unconjugated, Fc
Purity	95%
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-Fc, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	80.9 kDa
Description	Human DLL4, Fc Tag (DL4-H5259) is expressed from human 293 cells (HEK293). It contains AA Ser 27 - Pro 524 (Accession # NP_061947.1).
Background	Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.
Molecule	DLL4
Exp Region	Ser 27 - Pro 524
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 80.9 kDa. The protein migrates as 95-100 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	0.01 EU per μg
Buffer	100 mM Glycine, 150 mM NaCl, 25 mM Arginine, 50 mM Tris, pH7.5
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

DL4-H5259-500ug-datasheet.pdf

DL4-H5259-500ug-safety-datasheet.pdf