BSG Polyclonal Antibody

BSG

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

30kDa, 40-60kDa

BSG, also named as 5F7, Basigin, EMMPRIN, TCSF and CD147, plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS).CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. It seems to be a receptor for oligomannosidic glycans. CD147 is a receptor of CypA, inducing matrix metalloproteinase expression and mediating the degradation of the extracellular matrix, plays an important role in tumorigenesis and invasion in oral cancer. It has been considered as an objective and effective marker to predict invasion and prognosis in various cancers.

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

WB 1:1000-1:2000; IHC 1:100-1:300

Polyclonal

Polyclonal Antibodies