« Zurück
Startseite /
AF/LE Purified Anti-Mouse CD54 Antibody[YN1/1.7.4]

AF/LE Purified Anti-Mouse CD54 Antibody[YN1/1.7.4]

ArtNr	E-AB-F10180-25ug
Hersteller	Elabscience
Menge	25 ug
Quantity options	1 mg 100 mg 100 ug 25 mg 25 ug 50 ug 500 ug 5 mg
Kategorie	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Hematology Myeloma Cell Biology Cell Movement Cell Adhesion Flow Cytometry Immunofluorescence Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	FC
Clon	YN1/1.7.4
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Intercellular adhesion molecule 1, Icam1, MALA-2, MyD10, CD54, Icam-1,
Versandbedingung	Gekühlt
Gefahren-Info	Comply with cargo safety certificate
Lieferbar
Manufacturer - Applications	FCM
Manufacturer - Category	Flow Cytometry Antibodies
Manufacturer - Isotype	Rat IgG2b, κ
Manufacturer - Targets	CD54
Manufacturer - Conjugate / Tag	None (AF/LE)
Shipping Temperature	Ice bag
Storage Conditions	Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Background	CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.
Concentration	≥1 mg/mL
Buffer	Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.
Abbreviation	CD54
Clonality	Monoclonal
Usage	Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.