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MCTS1 Polyclonal Antibody

MCTS1 Polyclonal Antibody

ArtNr	E-AB-15193-120
Hersteller	Elabscience
Menge	120 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Kategorie	Oncology Neuroscience Metabolism Diabetes Glucose Homeostasis Neural Signaling Antibodies By Cell Type Carcinoma Hematology Lymphoma Obesity Immunohistochemistry Western Blot ELISA Primary Antibodies By Organ Colorectal Cancer Breast Cancer Testicular & Prostate Cancer
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	FLJ39637, Malignant T cell-amplified sequence 1, MCT 1, MCT-1, MCT1, MCTS 1, MCTS1, MCTS1, Multiple copies T cell malignancies 1, Multiple copies T cell malignancies, Multiple copies T-cell malignancies, Oncogene MCT 1, Oncogene MCT1
Similar products	MCT1, MCTS1, FLJ39637, MCT-1, MCT 1, MCTS 1, Oncogene MCT 1, Oncogene MCT1, Malignant T cell-amplified sequence 1, Multiple copies T cell malignancies 1, Multiple copies T cell malignancies, Multiple copies T-cell malignancies
Versandbedingung	Gekühlt
Gefahren-Info	Comply with cargo safety certificate
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	MCTS1
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	21kDa
Manufacturer - Research Areas	Cancer
Background	MCTS1 (malignant T cell amplified sequence 1), also known as MCT1, is a 181 amino acid protein that is ubiquitously expressed and localizes to the cytoplasm of cells. MCTS1 may play a role in cell cycle regulation by decreasing cell doubling time and by shortening the duration of G1 transit time and G1/S transition. The protein level of Cdk4 and Cdk6 kinases activity and cyclin D1 is enhanced by expression of MCTS1. As a translation enhancer, MCTS1 recruits DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile. MCTS1 promotes lymphoid tumor development and contributes to the pathogenesis and progression of breast cancer. MCTS1 positively regulates phosphorylation of ERK1 and ERK2.
Concentration	0.2 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:200-1:1000; IHC 1:100-1:300
Santa Cruz #	sc-168563
Abbreviation	MCTS1
Clonality	Polyclonal
Immunogen	Recombinant protein of human MCTS1
Category ID III	Polyclonal Antibodies

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