CA9 Monoclonal Antibody

CA IX

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

35-38kDa

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation.

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

WB 1:1000-1:3000; IHC 1:50-300; IF 1:50-1:200

Monoclonal

Monoclonal Antibodies