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Cleaved-CASP3 p12 (D175) Polyclonal Antibody

Cleaved-CASP3 p12 (D175) Polyclonal Antibody

ArtNr	E-AB-30003-200
Hersteller	Elabscience
Menge	200 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Immunofluorescence Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IF, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	https://www.nature.com/articles/s41590-022-01166-6 https://static.frontiersin.org/articles/10.3389/fmolb.2022.816510/full https://www.frontiersin.org/articles/10.3389/fphar.2021.646953/full?utm_source=S-TWT&utm_medium=SNET&utm_campaign=ECO_FPHAR_XXXXXXXX_auto-dlvrit https://www.worldscientific.com/doi/abs/10.1142/S0192415X21500245 https://www.sciencedirect.com/science/article/pii/S094471131630191X
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	A830040C14Rik, Apopain, CASP-3, CASP3, CASP3, Casp3a, Caspase 3, Caspase 3, apoptosis-related cysteine peptidase, Caspase 3, apoptosis-related cysteine protease, Caspase 3, apoptosis-related cysteine protease a, Caspase-3 subunit p12, CC3, CPP-32, CPP32, CPP32B, Cysteine protease CPP32, EC 3.4.22.56, LICE, mldy, OTTHUMP00000165052, OTTHUMP00000165053, OTTHUMP00000165054, PARP cleavage protease, Procaspase3, Protein Yama, SCA 1, SCA-1, SREBP cleavage activity 1, Yama
Similar products	CASP3, CPP32, Apopain, Cysteine protease CPP32, Protein Yama, SREBP cleavage activity 1, Caspase-3 subunit p12, CC3, LICE, CASP-3, CPP-32, SCA-1, Caspase 3, apoptosis-related cysteine protease, CPP32B, PARP cleavage protease, Yama, A830040C14Rik, mldy, SCA 1, OTTHUMP00000165054, Procaspase3, Casp3a, apoptosis-related cysteine peptidase, apoptosis-related cysteine protease a, EC 3.4.22.56, OTTHUMP00000165052, OTTHUMP00000165053
Versandbedingung	Gekühlt
Gefahren-Info	Comply with cargo safety certificate
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	Cleaved-Caspase-3 p12 (D175)
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	32kDa
Observed Molecular Weight	20+35kDa
Manufacturer - Research Areas	Cancer, Cell Biology, Metabolism, Neuroscience
Background	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
Concentration	1mg/mL
Buffer	PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-2000; IHC 1:50-300; IF 1:50-300
Abbreviation	Cleaved-Caspase-3 p12 (D175)
Clonality	Polyclonal
Immunogen	Synthesized peptide derived from the Internal region of human Caspase-3 p12
Category ID III	Polyclonal Antibodies

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