« Zurück
Startseite /
IkB alpha Polyclonal Antibody

IkB alpha Polyclonal Antibody

ArtNr	E-AB-70089-200
Hersteller	Elabscience
Menge	200 uL
Quantity options	120 uL 200 uL 60 uL
Kategorie	Oncology Metabolism Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Primary Antibodies By Organ Colorectal Cancer
Typ	Antibody Polyclonal
Applikationen	IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8061328/
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	I kappa B alpha, I-kappa-B-alpha, IkappaBalpha, IkB-alpha, IKBA, IKBA, IKBalpha, MAD 3, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha, NF-kappa-B inhibitor alpha, NFKBI, NFKBIA, Nuclear factor of kappa light chain gene enhancer in B cells, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha
Similar products	IkB-alpha, NFKBIA, MAD3, IKBA, NFKBI, NF-kappa-B inhibitor alpha, I-kappa-B-alpha, Major histocompatibility complex enhancer-binding protein MAD3, IkappaBalpha, I kappa B alpha, IKBalpha, MAD 3, NF kappa B inhibitor alpha, Nuclear factor of kappa light chain gene enhancer in B cells, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha
Versandbedingung	Gekühlt
Gefahren-Info	Comply with cargo safety certificate
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	IkB alpha
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas	Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction
Background	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA, synonyms: IKBA, MAD-3, NFKBI). NFKB1 or NFKB2 is bound to REL, RELA , or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime.
Concentration	1.3 mg/mL
Buffer	PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Purification Method	Affinity purification
Recommended Dilution	IHC 1:200-1:800
Abbreviation	IkB alpha
Clonality	Polyclonal
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse IKBα
Category ID III	Polyclonal Antibodies

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.