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Phospho-IkB alpha (Ser32/S36) Polyclonal Antibody

ArtNr E-AB-20911-20
Hersteller Elabscience
Menge 20 uL
Quantity options 120 uL 20 uL 200 uL 60 uL
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IF, IHC-P
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
Citations https://www.sciencedirect.com/science/article/pii/S0753332223000823
https://pubs.acs.org/doi/abs/10.1021/acs.jafc.2c04970
https://www.sciencedirect.com/science/article/pii/S0014299921005859
https://onlinelibrary.wiley.com/doi/abs/10.1111/odi.14218
https://journals.sagepub.com/doi/abs/10.1177/0960327121993224
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320209/
https://onlinelibrary.wiley.com/doi/abs/10.1111/jfbc.13876
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias I kappa B alpha, I-kappa-B-alpha, IkappaBalpha, IkB-alpha, IKBA, IKBA, IKBalpha, MAD 3, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha, NF-kappa-B inhibitor alpha, NFKBI, NFKBIA, Nuclear factor of kappa light chain gene enhancer in B cells, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha
Similar products IkB-alpha, NFKBIA, MAD3, IKBA, NFKBI, NF-kappa-B inhibitor alpha, I-kappa-B-alpha, Major histocompatibility complex enhancer-binding protein MAD3, IkappaBalpha, I kappa B alpha, IKBalpha, MAD 3, NF kappa B inhibitor alpha, Nuclear factor of kappa light chain gene enhancer in B cells, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha
Versandbedingung Gekühlt
Gefahren-Info Comply with cargo safety certificate
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Targets
IκB-α (phospho Ser32/36)
Shipping Temperature
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
36kDa
Observed Molecular Weight
34kDa
Manufacturer - Research Areas
Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction
Background
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Concentration
1 mg/mL
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method
Affinity purification
Recommended Dilution
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000
Abbreviation
IκB-α (phospho Ser32/36)
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human IκB-α around the phosphorylation site of Ser32/36
Category ID III
Acetyl/Phospho/Methyl Antibodies

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 uL
Lieferbar: In stock
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