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FADD Polyclonal Antibody

FADD Polyclonal Antibody

ArtNr	E-AB-10318-60
Hersteller	Elabscience
Menge	60 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Kategorie	Oncology Metabolism Cholesterol & Lipid Metabolism Antibodies By Cell Type Carcinoma Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Enzymes Fatty Acid Synthesis Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	https://www.scirp.org/journal/paperinformation.aspx?paperid=90472 https://www.scirp.org/journal/paperinformation.aspx?paperid=89457
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	FADD, FADD protein, FADD, Fas (TNFRSF6) associated via death domain, Fas associated via death domain, Fas associating death domain containing protein, Fas associating protein, Fas associating protein with death domain, Fas TNFRSF6 associated via death domain, FAS-associated death domain protein, FAS-associating death domain-containing protein, GIG 3, GIG3, Growth inhibiting gene 3 protein, Growth-inhibiting gene 3 protein, H sapiens mRNA for mediator of receptor induced toxicity, Mediator of receptor induced toxicity, MGC8528, MORT 1, MORT1, Protein FADD
Similar products	FADD, MORT1, Protein FADD, Mediator of receptor induced toxicity, FAS-associated death domain protein, FAS-associating death domain-containing protein, Growth-inhibiting gene 3 protein, GIG3, MGC8528, FADD protein, Fas TNFRSF6 associated via death domain, Fas associated via death domain, Fas associating death domain containing protein, Fas associating protein, Fas associating protein with death domain, GIG 3, Growth inhibiting gene 3 protein, H sapiens mRNA for mediator of receptor induced toxicity, MORT 1, Fas (TNFRSF6) associated via death domain
Versandbedingung	Gekühlt
Gefahren-Info	Comply with cargo safety certificate
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	FADD
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	23kDa
Research Areas	Cancer, Cell Biology
Background	The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
Concentration	0.5 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:1000-1:5000; IHC 1:50-1:100
Santa Cruz #	sc-6035, sc-5559
Abbreviation	FADD
Clonality	Polyclonal
Immunogen	Recombinant protein of human FADD
Category ID III	Polyclonal Antibodies

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