PIM2 Polyclonal Antibody

PIM2

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

IHC 1:50-1:200

PIM2

Recombinant protein of human PIM2