LRP5 Polyclonal Antibody

LRP5

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

IHC 1:100-1:300

LRP5

Synthetic peptide of human LRP5