TNFRSF13C Polyclonal Antibody

TNFRSF13C

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

IHC 1:50-1:200

TNFRSF13C

Synthetic peptide of human TNFRSF13C