CBS Polyclonal Antibody

CBS

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

61kDa

The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene.

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

IF 1:50-1:200

Polyclonal

Polyclonal Antibodies