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(KO Validated) SMARCA4 Polyclonal Antibody

ArtNr E-AB-60619-200
Hersteller Elabscience
Menge 200 uL
Quantity options 120 uL 200 uL 60 uL
Kategorie
Typ Antibody Polyclonal
Applikationen IF
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias BAF190, BAF190A, BRG1, CSS4, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2, hSNF2b, SMARCA4
Similar products SMARCA4, SNF2LB, SWI2, member 4, SWI/SNF related, matrix associated, BAF190, SNF2, BRG1, SNF2L4, hSNF2b, ATP-dependent helicase SMARCA4, actin dependent regulator of chromatin, SMCA4, subfamily a, Global transcription activator homologous sequence, ATP dependent helicase SMARCA4, BAF 190, BAF190A, Brahma protein like 1, BRG1 associated factor 190A, BRG1 protein, BRM/SWI2 related gene 1, Homeotic gene regulator, Mitotic growth and transcription activator, Nuclear protein GRB1, Protein brahma homolog 1, Protein BRG1, SMARC A4, SNF2 beta, SNF2 like 4, SNF2B, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 4, Transcription activator BRG1, BRG1-associated factor 190A, Protein BRG-1
Versandbedingung Gekühlt
Gefahren-Info Comply with cargo safety certificate
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Targets
SMARCA4
Shipping Temperature
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
181kDa/184kDa
Observed Molecular Weight
190kDa
Manufacturer - Research Areas
Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Stem Cells
Background
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Concentration
1mg/mL
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method
Affinity purification
Recommended Dilution
IF 1:50-1:200
Abbreviation
SMARCA4
Clonality
Polyclonal
Immunogen
A synthetic peptide of human SMARCA4 (NP_003063.2).
Category ID III
Polyclonal Antibodies

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 uL
Lieferbar: In stock
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