WHSC1 Polyclonal Antibody

WHSC1

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

80kDa, 152kDa

This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4; 14)(p16.3; q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

IHC 1:50-1:200

Polyclonal

Polyclonal Antibodies