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XRCC1 Polyclonal Antibody

XRCC1 Polyclonal Antibody

ArtNr	E-AB-64012-60
Hersteller	Elabscience
Menge	60 uL
Quantity options	120 uL 200 uL 60 uL
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Sarcoma Cell Biology Adenocarcinoma Cytoskeleton Western Blot Primary Antibodies By Organ Renal Cancer small GTPases Rab Subfamily
Typ	Antibody Polyclonal
Applikationen	IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	XRCC1, RCC
Similar products	XRCC1, complementing defective, RCC, DNA repair protein XRCC1, repair in Chinese hamster, Xrcc1, X ray repair, X-ray repair cross-complementing protein 1, X ray repair complementing defective repair in chinese hamster, X ray Repair Complementing Defective Repair in Chinese Hamster Cells, X ray repair complementing defective repair in chinese hamster cells 1, X ray repair cross complementing 1, X ray repair cross complementing protein 1, XRCC 1
Versandbedingung	Gekühlt
Gefahren-Info	Comply with cargo safety certificate
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	XRCC1
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	69kDa
Observed Molecular Weight	70kDa
Research Areas	Cancer, Epigenetics and Nuclear Signaling, Metabolism
Background	The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Concentration	1mg/mL
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Affinity purification
Recommended Dilution	IF 1:50-1:200
Abbreviation	XRCC1
Clonality	Polyclonal
Immunogen	Recombinant fusion protein of human XRCC1 (NP_006288.2).
Category ID III	Polyclonal Antibodies

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